PROTEIN CRYSTALS IN ADENOVIRUS TYPE 5-INFECTED CELLS: REQUIREMENTS FOR INTRANUCLEAR CRYSTALLOGENESIS, STRUCTURAL AND FUNCTIONAL ANALYSIS.

Protein crystals in Adenovirus type 5-infected cells: requirements for intranuclear crystallogenesis, structural and functional analysis.

Intranuclear crystalline inclusions have been observed in the nucleus of epithelial cells infected with Adenovirus serotype 5 (Ad5) at late steps of the virus life cycle.Using immuno-electron microscopy and confocal microscopy of cells infected with various Ad5 recombinants modified in their penton base or fiber domains, we found that these inclusi

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Maternal vaccination against RSV can substantially reduce childhood mortality in low-income and middle-income countries: A mathematical modeling study

Background: Respiratory syncytial virus (RSV) is a leading cause of childhood mortality in infants below 6 months of age.In low-income and middle-income countries (LMICs), the public health burden is substantial and resources are limited.It is critical to inform decision makers about effectiveness of new interventions.Methods: We developed a mathem

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A multi-criteria comparison of mobile applications built with the use of Android and Flutter Software Development Kits

This publication presents a multi-criteria comparison of two mobile applications built with the use of Android and Flutter SDK.The Electrolyte former has been implemented with Kotlin and the latter with Dart.The benchmarking process examines factors such as execution time and CPU usage during data and disk operations.During the analysis, attention

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Western lifestyle as a driver of dysbiosis in colorectal cancer

Landmark discoveries in the gut microbiome field have paved the way for new research aimed at illuminating the influence of microbiota in colorectal cancer.A major challenge is to account for the effect of inherently variable Basil environmental factors on the host and the gut microbiome, while concurrently determining their contribution to carcino

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